Furosap® (Fenugreek Seed Extract)

A clinically studied, standardised fenugreek seed extract rich in furostanolic saponins

Introduction

Furosap® is a highly standardised extract of fenugreek seed (Trigonella foenum-graecum L.), developed to deliver a consistent and well-characterised profile of furostanolic saponins, including the key marker compound protodioscin.

Fenugreek has a long history of traditional use, but Furosap® represents a modern, evidence-driven approach — combining botanical heritage with contemporary analytical testing and human clinical research.

Botanical identity and standardisation

Botanical name: Trigonella foenum-graecum L.

Plant part used: Seed

Extract type: Standardised fenugreek seed extract

Natural plant materials can vary due to growing conditions, harvest timing, and processing. To address this variability, Furosap® is standardised to defined active fractions to ensure batch-to-batch consistency and alignment with the material evaluated in published human studies.

The extract is characterised for:

• • Protodioscin, a furostanolic saponin commonly used as a quality marker
  • Total furostanolic saponins, representing the broader active phytochemical profile

Composition and analytical quality

Furosap® is assessed using laboratory techniques routinely applied to high-quality botanical extracts.

Key characteristics

• • Light brown to brown powder
  • High water solubility
  • Low moisture content, supporting stability

Active compound profile

• • Protodioscin: ≥20% (typical results ~23%)
  • Total furostanolic saponins: ≥45% (typical results ~55%)

These values are determined using high-performance liquid chromatography (HPLC), ensuring the extract consistently meets its defined specification.

Analytical Characterisation & Ingredient Verification

Furosap® is characterised using analytical techniques commonly applied to high-quality botanical extracts to confirm identity, composition, and consistency.

Active compound profile

The extract is standardised to defined levels of furostanolic saponins, including the key marker compound protodioscin. These compounds are quantified using high-performance liquid chromatography (HPLC), allowing precise measurement of active constituents and ensuring consistency with the extract profile used in published human studies.

Consistency and repeatability

Chromatographic analysis produces a characteristic chemical “fingerprint” for the extract. Across repeated analyses, the key marker compounds appear at consistent positions with stable relative intensity. This demonstrates that the extract behaves predictably during testing and maintains a repeatable composition from batch to batch.

Identity, purity, and quality controls

In addition to active compound verification, the ingredient is assessed against defined quality criteria, including:

• • Confirmation of botanical identity
  • Physical characteristics and solubility
  • Testing for heavy metals and residual solvents
  • Microbiological quality parameters suitable for food supplements

Together, these measures confirm that Furosap® meets its defined specification and is suitable for use in high-quality supplement formulations.

Human clinical research

Testosterone and male vitality

Human clinical studies conducted by academic and clinical research groups in India, and published in peer-reviewed journals such as the International Journal of Medical Sciences, have evaluated Furosap® in healthy adult men.

• • Increases in free and total testosterone markers
  • Improvements in subjective measures related to male vitality and wellbeing
  • No adverse effects on standard safety markers

Male reproductive health

Clinical investigations carried out by medical researchers working with hospital-based laboratories examined sperm parameters in healthy volunteers.

Reported outcomes included improvements in:

• • Sperm concentration
  • Motility
  • Morphology

Body composition and physical performance

A randomised, double-blind, placebo-controlled study published in Functional Foods in Health and Disease investigated Furosap® supplementation in resistance-trained men.

• • Increases in lean body mass
  • Improvements in serum testosterone markers compared with placebo

Registered clinical evaluation

Furosap® has also been evaluated within registered clinical trial frameworks, including listings on ClinicalTrials.gov, reflecting transparent and structured investigation under recognised research standards.

Safety and tolerability

Across published human studies, Furosap® has shown a favourable safety profile when consumed at the studied intake levels.

Safety assessments included:

• • Clinical chemistry
  • Liver and kidney markers
  • Adverse event monitoring

No serious adverse effects were reported in healthy adult populations during the study periods.

Potential benefits (evidence-led)

• • Male vitality and wellbeing as part of an active lifestyle
  • Healthy testosterone levels within the normal physiological range
  • Physical performance and body composition when combined with resistance training
  • Male reproductive health, including maintenance of healthy sperm parameters

Typical intake used in studies

Most human clinical studies investigating Furosap® have used a daily intake of 500 mg of the standardised extract, consumed consistently over periods of 8–12 weeks.

Summary

• • Defined standardisation to protodioscin and total furostanolic saponins
  • Demonstrated analytical consistency and repeatability
  • Multiple human clinical studies supporting male vitality, body composition, and reproductive health
  • A strong safety profile in healthy adult populations

For those seeking a fenugreek extract supported by both scientific research and robust quality verification, Furosap® represents a modern, evidence-based option.

References

1. Maheshwari A. et al. Efficacy of Furosap™, a novel Trigonella foenum-graecum seed extract, in enhancing testosterone level and improving sperm profile in male volunteers. International Journal of Medical Sciences, 2017.
2. Guo R. et al. Furosap®, a fenugreek seed extract, improves lean body mass and serum testosterone in a randomised, double-blind, placebo-controlled study. Functional Foods in Health and Disease, 2018.
3. Sankhwar S.N. et al. Safety and efficacy of Furosap®, a patented fenugreek seed extract, in healthy men. PubMed-indexed journal, 2021.
4. ClinicalTrials.gov. Evaluation of Furosap® in men with testosterone-related symptoms. NCT02748005.
5. Wankhede S. et al. Effect of Trigonella foenum-graecum supplementation on strength, body composition and hormonal profile. Journal of the International Society of Sports Nutrition, 2016.
6. Hayes L.D., Grace F.M. Herbal ingredients and testosterone: an evidence-based review. Advances in Nutrition, 2022.