GCB70® (Green Coffee Bean Extract)

A clinically evaluated green coffee bean extract standardised to 70% chlorogenic acids

Introduction

GCB70® is a standardised green coffee bean extract derived from Coffea species and enriched to contain high levels of chlorogenic acids, a group of naturally occurring polyphenols found in unroasted coffee beans. Unlike roasted coffee, where chlorogenic acids are significantly reduced, green coffee bean extracts provide a concentrated source of these bioactive compounds.

Green coffee bean extracts have been studied for their potential role in supporting body weight management, metabolic balance, and glycaemic markers. GCB70® has been evaluated in human clinical research exploring changes in body weight, body composition, waist circumference, and metabolic parameters in overweight individuals.

Botanical identity and standardisation

• Botanical source: Coffea robusta (green coffee beans)
• Plant part used: Unroasted coffee beans
• Extract type: Standardised green coffee bean extract
• Caffeine content: Low (≤2.0%)

Green coffee beans are naturally rich in chlorogenic acids, a family of polyphenolic compounds that include several caffeoylquinic acid isomers. GCB70® is standardised to ensure a consistent chlorogenic acid content, allowing alignment with material evaluated in human studies.

Composition and analytical quality

GCB70® is characterised using analytical techniques commonly applied to botanical extracts intended for food supplement use.

Key physical characteristics

• Pale yellow to brown coloured powder
• Characteristic odour and taste
• Particle size suitable for powder formulations
• Controlled bulk density, supporting uniform handling and dosing

Active compound profile

• Total chlorogenic acids: ≥70.0% (typical result: ~72.2%)
• 5-O-caffeoylquinic acid (5-CQA): ≥25.0% (typical result: ~28.8%)
• Caffeine: ≤2.0% (typical result: ~0.76%)

Active constituents are quantified using high-performance liquid chromatography (HPLC), ensuring the extract consistently meets its defined specification.

Analytical Characterisation & Ingredient Verification

GCB70® is assessed against defined identity, purity, and quality criteria to confirm suitability for use in high-quality supplement formulations.

Identity confirmation

Botanical identity is verified using thin-layer chromatography (TLC), with results confirming the presence of chlorogenic acids characteristic of green coffee bean extracts.

Consistency and repeatability

Chromatographic analysis produces a characteristic chemical “fingerprint” for the extract. Across repeated analyses, key chlorogenic acid components appear at consistent positions and relative intensities, demonstrating a repeatable and stable composition from batch to batch.

Purity and quality controls

In addition to active compound verification, the ingredient is assessed against established quality parameters, including:

• Moisture content (loss on drying) controlled to support stability
• Residual solvents monitored and maintained well below specified limits
• Microbiological quality compliant with food supplement criteria, with absence of pathogenic organisms
• Heavy metals (lead, arsenic, mercury, cadmium) tested and maintained within defined limits

Together, these measures confirm that GCB70® meets its defined specification and maintains a consistent analytical profile suitable for food supplement use.

Human clinical research

Body weight and metabolic outcomes

A controlled human clinical evaluation investigated the effects of GCB70® supplementation in overweight adults over a 12-week period. Participants consumed a total daily intake of 1,000 mg of the extract.

Reported outcomes included:

• Significant reductions in body weight and body mass index (BMI)
• Decreases in waist circumference, indicating changes in central adiposity
• Improvements in fasting blood glucose and HbA1c values
• Reductions in plasma leptin levels, consistent with changes in energy balance

All reported changes were statistically significant, and standard blood chemistry parameters remained within normal ranges throughout the study.

Safety observations

No serious adverse effects were reported during the intervention period, supporting a favourable tolerability profile for GCB70® when used at the studied intake level.

Potential benefits (evidence-led)

Based on its composition and available human research, GCB70® may support:

• Healthy body weight management as part of a balanced diet and lifestyle
• Body mass index (BMI) reduction in overweight individuals
• Waist circumference changes associated with metabolic health
• Healthy glycaemic markers, including fasting glucose and HbA1c within normal ranges
• Metabolic hormone balance, including leptin

These outcomes reflect findings from controlled human research and are dependent on overall dietary and lifestyle context.

Typical intake used in studies

Human clinical evaluation of GCB70® has used a daily intake of 1,000 mg, consumed consistently over a 12-week period.

Summary

GCB70® is a well-characterised, standardised green coffee bean extract enriched to ≥70% chlorogenic acids. Analytical verification confirms a consistent chlorogenic acid profile, low caffeine content, and compliance with purity and safety criteria. Human clinical research has demonstrated statistically significant improvements in body weight, BMI, waist circumference, and selected metabolic markers, alongside a favourable safety profile.

For those seeking a green coffee bean extract supported by analytical rigour and human clinical evaluation, GCB70® represents a transparent and evidence-based option.

GCB70® is available as a single-ingredient formulation here.