Resveratrol

ReserveNature® (Standardised Resveratrol Extract)

A premium resveratrol ingredient primarily supplied as trans-resveratrol from Japanese knotweed

Introduction

ReserveNature® is a premium resveratrol ingredient used in dietary supplement formulations. It is based on trans-resveratrol, a natural polyphenolic compound classified as a stilbenoid. Resveratrol is produced by various plants in response to stress and is found naturally in the skin of grapes, berries (including blueberries and raspberries), peanuts, and especially in Polygonum cuspidatum (Japanese knotweed).

ReserveNature® is recognised within the supplements industry as a high-purity source of resveratrol that is specified to contain ≥99.0% trans-resveratrol, with negligible levels of related impurities such as emodin (a common stilbene contaminant).

Botanical identity and standardisation

  • Compound: Resveratrol (3,5,4′-trihydroxy-trans-stilbene)
  • Source: Extracted from Polygonum cuspidatum (Japanese knotweed)
  • Extract type: Standardised polyphenolic extract
  • Primary isomer: Trans-resveratrol (biologically relevant form)
  • Specified purity: ≥99.0% trans-resveratrol (ReserveNature®)

Resveratrol is a natural stilbenoid polyphenol widely studied for its biochemical properties. It exists in cis and trans isomeric forms, with the trans form being the predominant and more stable form used in dietary supplements.

Composition and analytical quality

ReserveNature® is specified to contain ≥99.0% trans-resveratrol. The extract is characterised using chromatographic methods such as HPLC (High-Performance Liquid Chromatography) to confirm identity and quantify resveratrol content.

Analytical quality markers

  • High trans-resveratrol content: ≥99.0%
  • Low contaminant profile: Minimal related stilbenes (e.g. emodin) and other impurities
  • Standardised reference: Chromatographic identity and quantitation against pure resveratrol reference standards

These analytical parameters support consistency and compositional clarity.

Ingredient verification (identity and purity)

ReserveNature® is assessed against defined identity and purity criteria.

Chemical identity

Resveratrol is identified by chromatographic retention time and UV spectral characteristics that match authentic trans-resveratrol reference standards.

Chromatographic quantitation

HPLC or equivalent analytical methods confirm the percentage of trans-resveratrol, meeting or exceeding the ≥99.0% specification.

Purity profile

Analytical profiles demonstrate minimal levels of related stilbenes, isomers, and non-target compounds. Absence of unexpected contaminants is confirmed.

Resveratrol: biochemical context

Resveratrol is a small polyphenolic molecule that functions in plants as a phytoalexin — a compound produced in response to environmental stressors. As a botanical polyphenol, it has been extensively studied in laboratory, animal, and human research contexts.

Human research context

A large body of research has examined resveratrol in various human clinical settings, although studies vary widely in design, dose, and outcomes.

  • Metabolic markers: Investigated in relation to glucose metabolism and insulin sensitivity
  • Cardiovascular markers: Studied for effects on vascular and circulatory parameters
  • Cognition and mood: Evaluated in diverse populations with variable results
  • Oxidative stress response: Explored due to resveratrol’s polyphenolic structure

The overall evidence base remains heterogeneous, with variation in population, dosage, and outcome measures.

Safety and tolerability

Human clinical studies have generally reported resveratrol to be well tolerated at commonly used intake levels. Mild, transient gastrointestinal effects have been reported at higher intakes in some studies.

Potential benefits (evidence-led)

Based on the current state of research, resveratrol has been investigated in relation to:

  • Metabolic and glucose-related markers
  • Cardiovascular health parameters
  • Oxidative stress pathways
  • Cognitive and mood-related outcomes

Typical intake and formulations

Resveratrol is commonly formulated in daily amounts ranging from 50 mg to 500 mg, depending on product design and regulatory considerations.

Summary

ReserveNature® is a premium resveratrol ingredient specified to contain ≥99.0% trans-resveratrol, extracted from Polygonum cuspidatum (Japanese knotweed). Analytical characterisation confirms identity and high purity, providing a clearly defined and consistent composition.

Resveratrol is available as a single-ingredient formulation here.